If Ohio St can get the ground game going and can control the clock, they could cover +11 and the game could go under 48.5.
If they cannot, it will be Miami in a blowout and the over. From a gambling perspective, I am gonna watch the first half, and play 2nd half money.
I don't see any way OSU wins, unless turnovers by Miami are the key. I would lean towards Miami, if I had to play before the game.